Eye development (vertebrate)
Ma, Li Department of Biology, University of Maryland, College Park, Maryland.
Jeffery, William R. Department of Biology, University of Maryland, College Park, Maryland.
- Genetic mechanisms of eye development
- Eye degeneration
- Lens signaling
- Genetic analysis of eye degeneration
- Links to Primary Literature
- Additional Readings
The vertebrate eye is an extraordinary organ in terms of its structure, function, and development. Vision is acquired during embryonic development as a result of the coordinated formation and growth of several different eye tissues. The mature eye consists of anterior and posterior sectors (Fig. 1). The major parts of the anterior sector are the cornea, anterior chamber, iris, and crystalline lens. The posterior sector consists of the posterior chamber, retina, and retinal pigment epithelium (RPE). Eye tissues are derived from three different embryonic sources. The lens and the external part of the cornea originate from the surface ectoderm. The interior part of the cornea and a part of the iris are derived from the neural crest. The retina, RPE, and the other part of the iris are formed from the optic vesicle, which is derived from the anterior neural ectoderm.
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