Homeotic (Hox) genes
McGinnis, William Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut.
- Links to Primary Literature
- Additional Readings
The genes whose defect allows formation of a normal plant or animal body structure or organ in place of another at an abnormal site. Examples of homeosis (also called homeotic transformation) are most obvious in insect appendages, where appendages that are characteristic of one segment, for example, the antennae on an insect head segment, are transformed into insect legs that normally develop only on trunk segments (see illustration). Similar examples of homeotic transformations can also occasionally be found in vertebrates where lumbar vertebrae are transformed into thoracic vertebrae, which then extend into rib processes, or in floral organs where petals are transformed into sepals. Homeotic transformations rarely occur in nature in living organisms, and are due to genetic defects in a class of proteins called homeotic proteins, the products of homeotic genes. In addition, homeotic transformations are due to the accidental or deliberate manipulation of homeotic gene expression so that homeotic proteins are produced in the wrong place or at the wrong time in developing plants and animals. See also: Gene; Pattern formation (biology)
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Its dedicated editorial team is led by Sagan Award winner John Rennie. Contributors include more than 9000 highly qualified scientists and 39 Nobel Prize winners.
MORE THAN 8500 articles and Research Reviews covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 17,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information