- Health Sciences
- Medicine and health science - general
- Neoadjuvant systemic therapy for breast cancer
Neoadjuvant systemic therapy for breast cancer
Seitelman, Eric D. Department of Surgery, Division of Surgical Oncology, Virginia Commonwealth University, Richmond, Virginia.
Bear, Harry D. Department of Surgery, Division of Surgical Oncology, Virginia Commonwealth University, Richmond, Virginia.
- Extent of resection
- Axillary node sampling
- Hormonal therapy
- Links to Primary Literature
- Additional Readings
The term neoadjuvant is used to describe therapy given prior to a planned surgical resection of a cancer with curative intent. Neoadjuvant systemic therapy (NST) has been explored in many different types of neoplasms, with varying success. Historically, breast cancer has been managed with primary surgery, followed by adjuvant (postoperative) chemotherapy, hormonal therapy, and/or radiation to decrease the chance of locoregional (restricted to a localized region of the body) and distant recurrence. NST for breast cancer was initially used to treat locally advanced breast cancer, which was considered inoperable. More recently, it has been increasingly applied to less advanced, operable breast cancer, and clinical trials have shown that it provides a range of benefits.
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Its dedicated editorial team is led by Sagan Award winner John Rennie. Contributors include more than 9000 highly qualified scientists and 39 Nobel Prize winners.
MORE THAN 8500 articles and Research Reviews covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 17,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information